Considerations When Using Cre-Driver Rodent Lines for Studying Ventral Tegmental Area Circuitry
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Considerations When Using Cre-Driver Rodent Lines for Studying Ventral Tegmental Area Circuitry
The use of Cre-driver rodent lines for targeting ventral tegmental area (VTA) cell types has generated important and novel insights into how precise neurocircuits regulate physiology and behavior. While this approach generally results in enhanced cellular specificity, an important issue has recently emerged related to the selectivity and penetrance of viral targeting of VTA neurons using severa...
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ژورنال
عنوان ژورنال: Neuron
سال: 2015
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2014.12.034